Systemic Histology: Trachea and Lung
- Describe the microscopic structure of trachea and lung
- Trachea:
- Mucous membrane → ciliated pseudostratified epithelium
- Submucosa → loose connective tissue, tracheal glands
- Trachealis muscle → smooth muscle
- Outer coat → adventitia
- Lung
- Parenchyma → alveoli, type I pneumocytes, type II pneumocytes
- Bronchi → ciliated pseudostratified epithelium
- Bronchioles → non-ciliated cuboidal epithelium
- Smooth muscle, cartilage → bronchi
- Correlate with their functions
- Trachea: protects airways, humidifies and warms air, traps dust particles
- Lung: gas exchange, oxygenation of blood, carbon dioxide removal
- Explain the applied aspect and correlate with histopathology
- Trachea
- Applied aspect: respiration, coughing
- Histopathology: tracheitis → inflammation of tracheal mucosa, tracheal cancer → abnormal cell growth in trachea
- Lung
- Applied aspect: gas exchange, oxygenation of blood
- Histopathology: pneumonia → inflammation of lung parenchyma, lung cancer → abnormal cell growth in lung tissue
Note: Histopathology involves the examination of tissues for disease diagnosis, and can be used to understand the effects of various conditions on the trachea and lung.