Cardiomyopathy
1. Definition Cardiomyopathy refers to diseases of the heart muscle (cardiac muscle) that can lead to the heart failing to pump blood properly. It's a serious condition that can be fatal if not treated.
2. Causes / Etiology Causes of cardiomyopathy can be genetic [inherited], viral infections [e.g. myocarditis], alcohol abuse, exposure to certain toxins [e.g. heavy metals, pesticides], poor diet, lack of physical activity, and certain medical conditions [e.g. diabetes, high blood pressure].
3. Types or Classification There are four main types of cardiomyopathy:
- Dilated Cardiomyopathy (DCM): The heart muscle becomes weak and the heart chambers get larger, making it harder for the heart to pump blood.
- Hypertrophic Cardiomyopathy (HCM): The heart muscle becomes thick, which can block blood flow and make it harder for the heart to pump.
- Restrictive Cardiomyopathy (RCM): The heart muscle becomes stiff, making it harder for the heart to fill with blood.
- Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC): The heart muscle in the right ventricle becomes damaged, leading to abnormal heart rhythms.
4. Pathology Step 1: The heart muscle cells become damaged due to various causes. Step 2 โ The damaged heart muscle cells lead to inflammation and scarring. Step 3 โ The inflammation and scarring cause the heart muscle to become weak and stiff. Step 4 โ The weakened and stiff heart muscle makes it harder for the heart to pump blood. Step 5 โ The reduced blood flow can lead to heart failure, arrhythmias, and even death.
5. Clinical Features General features:
- Shortness of breath
- Fatigue
- Swelling in the legs and feet
- Chest pain
- Coughing up pink frothy mucus Specific features:
- Dilated cardiomyopathy: Heart failure symptoms, heart murmur, and arrhythmias
- Hypertrophic cardiomyopathy: Heart failure symptoms, heart murmur, and arrhythmias
- Restrictive cardiomyopathy: Shortness of breath, fatigue, and swelling in the legs and feet
- Arrhythmogenic right ventricular cardiomyopathy: Abnormal heart rhythms, heart failure symptoms, and sudden cardiac death
6. Complications Acute complications:
- Heart failure
- Arrhythmias
- Cardiac arrest
- Sudden cardiac death Chronic complications:
- Heart failure
- Arrhythmias
- Cardiac remodeling
- Increased risk of stroke and other cardiovascular diseases
7. Diagnosis / Investigations Routine tests:
- ECG
- Chest X-ray
- Echocardiogram Special tests:
- Cardiac MRI
- Cardiac CT scan
- Cardiac catheterization
- Endomyocardial biopsy
8. Management General management:
- Lifestyle modifications [e.g. diet, exercise, stress management]
- Medications [e.g. diuretics, ACE inhibitors, beta blockers] Modern treatment:
- Implantable cardioverter-defibrillator (ICD)
- Pacemaker
- Heart transplant Dietary advice:
- Healthy diet rich in fruits, vegetables, and whole grains
- Limiting sodium and saturated fat intake
- Staying hydrated
9. Homeopathic Therapeutics
-
Aconite: For shock, fear, and anxiety
- Symptoms worsen at night
- Heart palpitations and irregular heartbeat
- Cold sweats and chills
-
Digitalis: For heart failure and arrhythmias
- Symptoms worsen with exertion
- Shortness of breath and fatigue
- Swelling in the legs and feet
-
Gelsemium: For fatigue, weakness, and lethargy
- Symptoms worsen with mental or physical exertion
- Heart palpitations and irregular heartbeat
- Cold sweats and chills
-
Ignatia: For anxiety, stress, and emotional instability
- Symptoms worsen with emotional stress
- Heart palpitations and irregular heartbeat
- Cold sweats and chills
-
Lachesis: For heart failure and arrhythmias
- Symptoms worsen with exertion
- Shortness of breath and fatigue
- Swelling in the legs and feet