Thyroid Swelling / Goitre
Definition
- Goitre is a swelling of the thyroid gland.
Types of Goitre
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Colloid Goitre
- Characterized by the presence of colloid within the thyroid gland.
- The thyroid gland is usually enlarged and firm.
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Toxic Goitre
- The thyroid gland is overactive and produces excess thyroid hormone.
- The thyroid gland is usually enlarged and firm.
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Retrosternal Goitre
- The thyroid gland extends below the sternum.
- It can cause respiratory symptoms due to the compression of the trachea.
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Substernal Goitre
- The thyroid gland extends below the clavicles.
- It can cause respiratory symptoms due to the compression of the trachea.
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Lymphocytic Goitre
- Characterized by the presence of lymphocytes in the thyroid gland.
- It is often associated with autoimmune thyroiditis.
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Follicular Goitre
- The thyroid gland is composed of follicles that are lined by follicular cells.
- It is often associated with thyroid cancer.
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Medullary Goitre
- The thyroid gland is composed of parafollicular cells.
- It is often associated with medullary thyroid carcinoma.
Causes of Thyroid Swelling (Goitre)
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Iodine Deficiency
- The thyroid gland is unable to produce thyroid hormone due to a lack of iodine.
- It is a common cause of goitre in areas where iodine-deficient salt is consumed.
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Thyroiditis
- Inflammation of the thyroid gland.
- It can cause the release of pre-formed thyroid hormone into the bloodstream.
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Thyroid Nodules
- Single or multiple nodules within the thyroid gland.
- They can cause the thyroid gland to become enlarged.
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Thyroid Cancer
- Cancer of the thyroid gland.
- It can cause the thyroid gland to become enlarged.
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Autoimmune Thyroiditis
- Inflammation of the thyroid gland due to an autoimmune response.
- It can cause the thyroid gland to become enlarged.
Clinical Features of Goitre
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Enlargement of the Thyroid Gland
- The thyroid gland is usually enlarged and firm.
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Respiratory Symptoms
- The compression of the trachea can cause respiratory symptoms such as dyspnea.
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Dysphagia
- The compression of the esophagus can cause dysphagia.
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Hoarseness of Voice
- The compression of the recurrent laryngeal nerve can cause hoarseness of voice.
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Paresthesia
- The compression of the recurrent laryngeal nerve can cause paresthesia.
Diagnosis of Goitre
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Physical Examination
- The thyroid gland is usually enlarged and firm.
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Imaging Studies
- Ultrasound, CT, or MRI scans can be used to evaluate the thyroid gland.
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Thyroid Function Tests
- Blood tests can be used to evaluate the thyroid function.
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Fine-Needle Aspiration Cytology (FNAC)
- A sample of thyroid tissue is obtained using a fine needle.
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Thyroid Scan
- A scan of the thyroid gland can be used to evaluate its function.
Investigations for Goitre
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Thyroid Function Tests (TFTs)
- Blood tests can be used to evaluate the thyroid function.
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Thyroid Antibodies
- Blood tests can be used to evaluate the presence of thyroid antibodies.
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Thyroid Scan
- A scan of the thyroid gland can be used to evaluate its function.
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Ultrasonography
- Ultrasound can be used to evaluate the thyroid gland.
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Computed Tomography (CT) Scan
- A CT scan can be used to evaluate the thyroid gland.
Complications of Goitre
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Respiratory Symptoms
- The compression of the trachea can cause respiratory symptoms such as dyspnea.
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Dysphagia
- The compression of the esophagus can cause dysphagia.
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Hoarseness of Voice
- The compression of the recurrent laryngeal nerve can cause hoarseness of voice.
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Paresthesia
- The compression of the recurrent laryngeal nerve can cause paresthesia.
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Thyroid Crisis
- A life-threatening complication of untreated hyperthyroidism.
Management of Goitre
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Surgery
- The removal of the thyroid gland.
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Radioactive Iodine
- The use of radioactive iodine to destroy the thyroid gland.
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Antithyroid Medications
- The use of medications to reduce the production of thyroid hormone.
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Thyroid Hormone Replacement Therapy
- The use of medications to replace the thyroid hormone.
Homoeopathic Medicines Used in Goitre
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Lycopodium
- Indicated in cases of goitre with symptoms of weakness and fatigue.
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Calcarea Carbonica
- Indicated in cases of goitre with symptoms of cold intolerance and weight gain.
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Selenium
- Indicated in cases of goitre with symptoms of fatigue and muscle weakness.
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Kali Iodatum
- Indicated in cases of goitre with symptoms of swelling and inflammation.
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Thyroidinum
- Indicated in cases of goitre with symptoms of thyroid dysfunction.
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Iodium
- Indicated in cases of goitre with symptoms of iodine deficiency.
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Calcarea Phosphorica
- Indicated in cases of goitre with symptoms of bone weakness and pain.
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Sanguinaria Canadensis
- Indicated in cases of goitre with symptoms of thyroid inflammation and pain.