Gross Anatomy of Liver
The liver is a vital organ in the body and is located in the upper right quadrant of the abdominal cavity.
Lobes of Liver
- The liver is divided into four lobes: right lobe, left lobe, caudate lobe, and quadrate lobe.
- The right lobe is the largest lobe and is divided into four segments (V, VI, VII, and VIII).
- The left lobe is divided into two segments (III and IV).
Surfaces of Liver
- The superior surface is in contact with the diaphragm.
- The inferior surface is in contact with the stomach, small intestine, and right kidney.
- The anterior surface is in contact with the anterior abdominal wall.
- The posterior surface is in contact with the right kidney and adrenal gland.
- The bare area is the part of the liver that is covered by peritoneum and is in contact with the diaphragm.
Segments of Liver
- The liver is divided into eight segments: I (caudate lobe), II (left lobe), III (left lobe), IV (left lobe), V (right lobe), VI (right lobe), VII (right lobe), and VIII (right lobe).
- Each segment has a specific blood supply and drainage.
Blood Supply of Liver
The liver receives its blood supply from two main sources: the hepatic artery and the portal vein.
Hepatic Artery
- The hepatic artery is a branch of the common hepatic artery.
- It supplies oxygenated blood to the liver.
- The hepatic artery is divided into three branches: right hepatic artery, left hepatic artery, and cystic artery.
Portal Vein
- The portal vein is a branch of the splenic vein and superior mesenteric vein.
- It supplies nutrient-rich blood to the liver.
- The portal vein is divided into two branches: right portal vein and left portal vein.
Hepatic Veins
- The hepatic veins are branches of the inferior vena cava.
- They drain deoxygenated blood from the liver.
- The hepatic veins are divided into three branches: right hepatic vein, middle hepatic vein, and left hepatic vein.
Anatomical Relationships
Diaphragm
- The diaphragm separates the liver from the thoracic cavity.
- The diaphragm is attached to the liver by the falciform ligament.
Gallbladder
- The gallbladder is a sac-like structure that stores bile.
- The gallbladder is attached to the liver by the cystic duct.
Stomach
- The stomach is a digestive organ that is located in the upper left quadrant of the abdominal cavity.
- The stomach is attached to the liver by the gastrohepatic omentum.
Pancreas
- The pancreas is a digestive organ that is located behind the stomach.
- The pancreas is attached to the liver by the pancreaticohepatic ligament.
Anatomical Relations
Relations of Liver
- The liver is in contact with the diaphragm, stomach, small intestine, and right kidney.
- The liver is separated from the thoracic cavity by the diaphragm.
- The liver is attached to the stomach by the gastrohepatic omentum.
Relations of Liver Lobes
- The right lobe is in contact with the stomach, small intestine, and right kidney.
- The left lobe is in contact with the stomach, small intestine, and left kidney.
Relations of Liver Segments
- Segment I (caudate lobe) is in contact with the inferior vena cava and right atrium.
- Segment II (left lobe) is in contact with the stomach and left kidney.
- Segment III (left lobe) is in contact with the stomach and left kidney.
- Segment IV (left lobe) is in contact with the stomach and left kidney.
- Segment V (right lobe) is in contact with the stomach, small intestine, and right kidney.
- Segment VI (right lobe) is in contact with the stomach, small intestine, and right kidney.
- Segment VII (right lobe) is in contact with the stomach, small intestine, and right kidney.
- Segment VIII (right lobe) is in contact with the stomach, small intestine, and right kidney.
Blood Supply of Liver Segments
Blood Supply of Segment I
- Segment I receives its blood supply from the hepatic artery and portal vein.
- The blood supply is divided into two branches: right branch and left branch.
Blood Supply of Segment II
- Segment II receives its blood supply from the left hepatic artery and left portal vein.
- The blood supply is divided into two branches: right branch and left branch.
Blood Supply of Segment III
- Segment III receives its blood supply from the left hepatic artery and left portal vein.
- The blood supply is divided into two branches: right branch and left branch.
Blood Supply of Segment IV
- Segment IV receives its blood supply from the left hepatic artery and left portal vein.
- The blood supply is divided into two branches: right branch and left branch.
Blood Supply of Segment V
- Segment V receives its blood supply from the right hepatic artery and right portal vein.
- The blood supply is divided into two branches: right branch and left branch.
Blood Supply of Segment VI
- Segment VI receives its blood supply from the right hepatic artery and right portal vein.
- The blood supply is divided into two branches: right branch and left branch.
Blood Supply of Segment VII
- Segment VII receives its blood supply from the right hepatic artery and right portal vein.
- The blood supply is divided into two branches: right branch and left branch.
Blood Supply of Segment VIII
- Segment VIII receives its blood supply from the right hepatic artery and right portal vein.
- The blood supply is divided into two branches: right branch and left branch.
Pathology of Liver
Causes of Liver Disease
- Viral hepatitis (e.g., hepatitis B, hepatitis C)
- Alcoholic liver disease
- Non-alcoholic fatty liver disease
- Primary biliary cirrhosis
- Primary sclerosing cholangitis
Clinical Features of Liver Disease
- Jaundice
- Abdominal pain
- Nausea and vomiting
- Fatigue
- Weight loss
Investigations of Liver Disease
- Liver function tests
- Ultrasound
- CT scan
- MRI
- Liver biopsy
Complications of Liver Disease
- Ascites
- Spontaneous bacterial peritonitis
- Hepatic encephalopathy
- Portal hypertension
- Liver failure
Management of Liver Disease
- Medications (e.g., antiviral medications, corticosteroids)
- Lifestyle modifications (e.g., weight loss, exercise)
- Surgery (e.g., liver transplant)
- Supportive care (e.g., fluid management, electrolyte replacement)
Homeopathic Therapeutic Medicines
Indications of Homeopathic Medicines
- Chelidonium majus: For liver congestion and jaundice.
- Taraxacum officinale: For liver and gallbladder inflammation.
- Silybum marianum: For liver and gallbladder protection.
- Cedrus deodora: For liver and kidney inflammation.
- Zingiber officinale: For liver and digestive system inflammation.
Clinical Anatomy of Liver
Clinical Anatomy of Liver Lobes
- The right lobe is the most common site for liver disease.
- The left lobe is smaller and contains the left hepatic artery and left portal vein.
- The caudate lobe is located behind the inferior vena cava and receives its blood supply from the hepatic artery and portal vein.
Clinical Anatomy of Liver Segments
- Segment I (caudate lobe) is the most posterior and superior segment.
- Segment II (left lobe) is the smallest segment and receives its blood supply from the left hepatic artery and left portal vein.
- Segment III (left lobe) is the second smallest segment and receives its blood supply from the left hepatic artery and left portal vein.
- Segment IV (left lobe) is the third smallest segment and receives its blood supply from the left hepatic artery and left portal vein.
- Segment V (right lobe) is the largest segment and receives its blood supply from the right hepatic artery and right portal vein.
- Segment VI (right lobe) is the second largest segment and receives its blood supply from the right hepatic artery and right portal vein.
- Segment VII (right lobe) is the third largest segment and receives its blood supply from the right hepatic artery and right portal vein.
- Segment VIII (right lobe) is the smallest segment and receives its blood supply from the right hepatic artery and right portal vein.