PANCOAST TUMOURS
Definition:
- Pancoast tumour is a type of lung cancer that originates in the upper part of the lung and extends into the thoracic cavity.
- These tumours are typically apical, located near the apex of the lung.
Clinical Features:
- Shoulder pain is a common symptom, often accompanied by numbness or weakness in the arm.
- Horner's syndrome can occur due to involvement of the sympathetic nerves, causing ptosis, miosis, and anhidrosis.
- Pancoast tumours can also cause arm swelling or weakness due to the involvement of the brachial plexus.
- Clubbing of the fingers can occur due to chronic hypoxia.
- Weight loss, fatigue, and cough are also common symptoms.
- Superior vena cava syndrome can occur if the tumour compresses the superior vena cava.
Types:
- Squamous cell carcinoma is the most common type of Pancoast tumour.
- Adenocarcinoma and large cell carcinoma are also common.
- Small cell carcinoma is rare.
Causes:
- The exact cause of Pancoast tumours is unknown, but smoking is a significant risk factor.
- Exposure to asbestos and radon has also been linked to an increased risk.
- Genetic predisposition may also play a role.
Investigations:
- Chest X-ray is often the first imaging modality used to diagnose Pancoast tumours.
- CT scan is essential for staging the tumour and assessing the extent of local invasion.
- PET scan can help determine the presence of metastatic disease.
- MRI is useful for assessing the involvement of the brachial plexus and other neural structures.
- Biopsy is necessary for histopathological diagnosis.
Complications:
- Superior vena cava syndrome is a life-threatening complication that requires emergency treatment.
- Brachial plexus neuropathy can cause significant morbidity.
- Horner's syndrome can occur due to involvement of the sympathetic nerves.
- Weight loss and fatigue are common complications.
Management:
- Surgical resection is the primary treatment for Pancoast tumours.
- Preoperative chemotherapy and radiotherapy can help reduce tumour size and improve resectability.
- Postoperative radiotherapy can help prevent local recurrence.
Indications for Surgical Management:
- Resection of the tumour is possible without compromising the function of the surrounding structures.
- The patient is a good surgical candidate with no significant comorbidities.
- The tumour is localized and has not spread to distant sites.
Surgical Steps:
- The patient is positioned in a supine position with the arm on the affected side abducted and externally rotated.
- The incision is usually made in the second intercostal space, parallel to the ribs.
- The pleura is opened, and the pulmonary artery is identified and dissected free.
- The superior vena cava is identified and mobilized, if necessary.
- The brachial plexus is dissected and resected, if necessary.
- The tumour is resected en bloc, along with any involved lymph nodes.
- The chest is closed, and the patient is extubated.
SUPERIOR VENA CAVA SYNDROME
Definition:
- Superior vena cava syndrome is a medical emergency that occurs when the superior vena cava is compressed or obstructed.
- This can lead to a decrease in venous return to the heart, causing symptoms such as facial swelling, arm swelling, and shortness of breath.
Clinical Features:
- Facial swelling is a common symptom, often accompanied by arm swelling.
- Shortness of breath can occur due to decreased venous return to the heart.
- Headache and confusion can occur due to increased intracranial pressure.
- Patients may experience nausea and vomiting.
Management:
- The patient is positioned in a supine position with the head of the bed elevated.
- A chest X-ray is taken to rule out any other causes of the symptoms.
- CT scan is essential for diagnosing the cause of the superior vena cava syndrome.
- Biopsy may be necessary to confirm the diagnosis.
- Treatment depends on the underlying cause, but may include:
- Endovascular stenting or balloon dilatation to relieve compression.
- Chemotherapy or radiotherapy to treat underlying cancer.
- Corticosteroids to reduce inflammation and swelling.
HOMOEOPATHIC THERAPEUTIC MEDICINES
- Arnica: For pain and swelling.
- Bryonia: For pain and swelling in the arm.
- Calcarea carbonica: For general symptoms of cancer, such as fatigue and weight loss.
- Conium: For weakness and numbness in the arm.
- Lachesis: For facial swelling and shortness of breath.
- Pulsatilla: For general symptoms of cancer, such as fatigue and weight loss.
- Silica: For general symptoms of cancer, such as fatigue and weight loss.
- Thuja: For general symptoms of cancer, such as fatigue and weight loss.
Indications:
- Arnica: For pain and swelling after surgery.
- Bryonia: For pain and swelling in the arm after surgery.
- Calcarea carbonica: For general symptoms of cancer, such as fatigue and weight loss.
- Conium: For weakness and numbness in the arm after surgery.
- Lachesis: For facial swelling and shortness of breath.
- Pulsatilla: For general symptoms of cancer, such as fatigue and weight loss.
- Silica: For general symptoms of cancer, such as fatigue and weight loss.
- Thuja: For general symptoms of cancer, such as fatigue and weight loss.
Dosage:
- Arnica: 3-5 drops, 3 times a day.
- Bryonia: 3-5 drops, 3 times a day.
- Calcarea carbonica: 3-5 drops, 3 times a day.
- Conium: 3-5 drops, 3 times a day.
- Lachesis: 3-5 drops, 3 times a day.
- Pulsatilla: 3-5 drops, 3 times a day.
- Silica: 3-5 drops, 3 times a day.
- Thuja: 3-5 drops, 3 times a day.